In Vitro-In Silico-Based Mixture Risk Assessment
We use ToxCast in vitro assays in combination with computational in vitro to in vivo extrapolation (IVIVE) modeling and human exposure data to conduct an in vitro- and in silico-based mixture risk assessment of combined exposure to multiple chemicals.
Integrating Diet Survey and Population Modeling into Risk and Benefit Assessment
We conduct the risk and benefit assessment of a chemical based on internal dose metric by integrating total diet study and population toxicokinetic modeling.
Integrating Human Biomonitoring Data and Population Modeling into Risk Assessment
We integrate human biomonitoring data with human PBPK modeling and population data-based dose–response analysis for exposure and human health risk assessment of environmental chemicals.